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This report examines a case of cerebral toxoplasmosis in a renal transplant recipient, emphasizing the need for awareness of this rare complication.

March 15, 2026LifeOpen Access

Cerebral Toxoplasmosis in a Renal Transplant Recipient—A Rare Complication

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Case report shows diagnostic challenges of cerebral toxoplasmosis in renal transplant, indicating early anti-toxoplasma therapy improves outcomes.

This report examines a case of cerebral toxoplasmosis in a renal transplant recipient, emphasizing the need for awareness of this rare complication.
Descriptive case report
Patient maintained on immunosuppressive therapy with cyclosporine, mycophenolate mofetil, and prednisone
Polymerase chain reaction and histopathological analysis for diagnosis
Treatment with pyrimethamine, sulfadiazine, and leucovorin along with immunosuppressive therapy adjustment
Patient presented with neurological symptoms and was diagnosed with cerebral toxoplasmosis
Histopathological analysis revealed Toxoplasma gondii bradyzoites
Neurological improvement and radiological regression noted after treatment
Patient later succumbed to multidrug-resistant urosepsis

Mihaljević et al. (2026) studied this question.

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Case report shows diagnostic challenges of cerebral toxoplasmosis in renal transplant, indicating early anti-toxoplasma therapy improves outcomes.