Tattoo‐Associated Uveitis: A Case Series Highlighting Diverse Clinical Presentations and Therapeutic Challenges

Tattoo‐associated uveitis is a rare inflammatory condition linked to tattooed skin, often presenting as bilateral anterior uveitis with complications such as macular edema and retinal vasculitis. Although some cases are associated with systemic sarcoidosis, others result from hypersensitivity or localized granulomatous reactions to tattoo pigments. This case series highlights five patients aged 20–39 with varying severities of uveitis, all requiring systemic immunosuppression, including methotrexate or adalimumab. Tattoo inflammation may precede or follow ocular symptoms, complicating diagnosis. The findings emphasize the need to recognize tattoos as potential triggers of recurrent uveitis and the importance of tailored treatment to preserve visual acuity.