Findings show early unclamping decreases warm ischemia time in laparoscopic partial nephrectomy, suggesting improved oncologic outcomes.
Early unclamping in LPN is a feasible and safe technique that reduces WIT without compromising visibility during tumor resection or renorrhaphy. This strategy theoretically supports favorable functional and oncologic outcomes, though definitive evidence is limited by the lack of long-term follow-up. Larger prospective studies are needed to confirm these potential benefits.
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Alkassis et al. (2026) studied this question.
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