Coronary Endothelial Dysfunction Is Associated With Major Depressive Disorder in Men With Chest Pain and Nonobstructive Coronary Artery Disease

Key Points

• The study aims to explore the link between coronary endothelial dysfunction and major depressive disorder in men with chest pain and nonobstructive coronary artery disease.
• Observational study design
• Focus on men with chest pain and nonobstructive coronary artery disease
• Investigation of macrovascular coronary endothelial dysfunction and its association with major depressive disorder
• Significant association found between macrovascular coronary endothelial dysfunction and incident major depressive disorder
• Endothelial dysfunction identified as a potential biomarker for risk assessment of major depressive disorder