Retrospective cohort study shows increased withdrawal odds with morphine in children with bronchiolitis, indicating a need for careful opioid weaning strategies.
Patients with a higher cumulative IV opioid dose, an IV opioid wean in the preceding 8-12 hours, and greater than or equal to 2 CCC-V2 categories had the highest odds of withdrawal in this single-center study. Morphine was associated with increased odds of withdrawal as well.
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Shanklin et al. (2026) studied this question.
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