Elevated DOCK4 expression improves survival in clear cell renal cell carcinoma, suggesting a therapeutic target for immunotherapy strategies.
DOCK4 is a promising prognostic biomarker in ccRCC, with high expression indicating favorable pathologic staging and improved survival. Its role in modulating the TIME suggests that DOCK4 could also serve as a therapeutic target, potentially guiding future immunotherapy strategies for this aggressive malignancy.
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He et al. (2026) studied this question.
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