Draft genome sequence of CTX-M-5 variant-carrying Kluyvera ascorbata isolated from river water in Kumamoto, Japan

Takatoshi Yamamoto; Chie Shitada; Tatsuya Kawaguchi; Shinji Narahara; Makoto Kuroda

doi:10.1128/mra.01511-25

March 13, 2026Microbiology Resource AnnouncementsOpen Access

Draft genome sequence of CTX-M-5 variant-carrying Kluyvera ascorbata isolated from river water in Kumamoto, Japan

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Key Points

This research aims to sequence the genome of a CTX-M-5 variant-carrying Kluyvera ascorbata isolated from river water.
Isolated strain KHSU-R5-7 from Shirakawa River in Kumamoto, Japan.
Conducted draft genome sequencing of the isolate.
Analyzed genes related to antimicrobial resistance.
Identified the presence of CTX-M-5 variant genes.
Demonstrated the occurrence of extended-spectrum β-lactamases in environmental settings.

Implication

Genome sequence reveals extended-spectrum β-lactamases in Kluyvera ascorbata from river water, indicating environmental antimicrobial resistance.

Abstract

The genus Kluyvera is presumed to be the original source of blaCTX-M genes, which encode one of the most prevalent extended-spectrum β-lactamases. We report the draft genome sequence of Kluyvera ascorbata strain KHSU-R5-7, a CTX-M-5 variant producing isolate obtained from Shirakawa River in Kumamoto, Japan.

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Cite This Study

Yamamoto et al. (2026) studied this question.

synapsesocial.com/papers/69b606c483145bc643d1cf98 https://doi.org/10.1128/mra.01511-25

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Draft genome sequence of CTX-M-5 variant-carrying Kluyvera ascorbata isolated from river water in Kumamoto, Japan

Key Points

Implication

Abstract

Discussion

Cite This Study

Draft genome sequence of CTX-M-5 variant-carrying Kluyvera ascorbata isolated from river water in Kumamoto, Japan

Key Points

Implication

Abstract

Discussion

Cite This Study

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