Definitional Heterogeneity and Clinical Outcomes in Infected Native Aortic Aneurysm: A Systematic Review and Meta-analysis

Karthigesu Aimanan; Ng Lee Mei; Pradeep Chand Chandran; Michael Arvind; Putera Mas Pian; Kumaraguru V K Pillay; Hanif Hussein; Kishen Raj Chandra Sakaran

doi:10.1016/j.jvsvi.2026.100399

March 1, 2026JVS-Vascular InsightsOpen Access

Definitional Heterogeneity and Clinical Outcomes in Infected Native Aortic Aneurysm: A Systematic Review and Meta-analysis

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Key Points

The study aims to synthesize evidence on infected native aortic aneurysm, focusing on diagnostic definitions and clinical outcomes.
Conducted systematic review and meta-analysis of studies from multiple databases.
Included studies reporting three or more cases of infected native aortic aneurysm.
Extracted data on diagnostic definitions, microbial profiles, operative strategies, and outcomes.
Performed random-effects meta-analyses for early mortality and reintervention rates.
Identified 63 eligible studies with high heterogeneity in diagnostic definitions.
Pooled early mortality rate was 20.3% and reintervention rate was 12%.
No significant difference in early mortality between open repair and endovascular repair was found.
Geographic variation in microbiology was observed, with Salmonella predominant in Asia.

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Implication

This systematic review evaluates clinical outcomes and definitions of infected native aortic aneurysm, indicating high early mortality rates and variability in microbiology.

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Cite This Study

Aimanan et al. (2026) studied this question.

synapsesocial.com/papers/69b64c67b42794e3e660dadc https://doi.org/10.1016/j.jvsvi.2026.100399

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Definitional Heterogeneity and Clinical Outcomes in Infected Native Aortic Aneurysm: A Systematic Review and Meta-analysis

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Definitional Heterogeneity and Clinical Outcomes in Infected Native Aortic Aneurysm: A Systematic Review and Meta-analysis

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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