Retention and Marginal Integrity of a Nanohybrid Flowable Composite Used as a Pit and Fissure Sealant: A Split-mouth Randomized Clinical Trial

resin-based sealant for retention rate and marginal integrity.Thus, the present randomized controlled clinical trial was conducted to compare the retention rate and marginal integrity of a nanohybrid IntroductIonDental caries remains a widespread lifestyle-related disease, resulting in substantial morbidity and affecting diverse populations globally. 1The multifactorial etiology of dental caries, coupled with its social impact, makes it a critical concern in dental public health.Despite a noted decline in overall caries prevalence due to interventions such as fluoride usage, oral health education, and preventive measures such as pit-and-fissure sealants, occlusal caries persists, particularly due to the anatomical complexity of molar pits and fissures favoring plaque retention. 2istorically, pit-and-fissure sealants have evolved from cyanoacrylates and polyurethanes to more advanced Bis-GMA resin, with progressive improvements in retention and sealing efficacy. 3The development of flowable composites introduced a new dimension in restorative dentistry.With lower viscosity and better adaptation, these materials offer advantages as pit-andfissure sealants, potentially improving both retention and marginal integrity compared to conventional options. 4ecent studies underscore the improved wear resistance and mechanical performance of nanohybrid flowable composites when used as sealants. 5However, clinical data comparing their performance to conventional resin-based sealants are limited.Pitand-fissure sealants depend on the technology used.Additionally, the deterioration of the attachment between the tooth and sealant may be the cause of resin-based fissure sealants' inability to be retained over time. 6No prior study has compared nanohybrid flowable composite resin (G-aenial Universal Flo) and conventional 1,