Barriers and Facilitators to Implementing Guideline Recommendations for Key Aspects of Familial Hypercholesterolemia Management in Australia: Primary Care Integration, Paediatric Management, and Treatment Adherence

MethodThree (3) 2-hour virtual focus groups were conducted as part of the 2022 Australasian FH Summit (29 October 2022).A purposive cross-section of key stakeholder groups was sought at the Summit.The focus groups were co-facilitated by an implementation scientist and a clinician, audio recorded, transcribed, and notes were taken by the facilitators.Transcripts were analysed inductively and deductively according to a template analysis using NVivo. ResultsThere was a total of 27 workshop attendees across the three groups (n=6-14 each).We identified 27 barriers and 28 facilitators on the topics of integration of care with general practice (nine barriers and eight facilitators), paediatric management (eight barriers and eight facilitators), and treatment adherence (10 barriers and 12 facilitators), categorised according to whether they were patient-related, provider-related, or system-related.Common barriers across the priority areas included a lack of knowledge and skills in FH and urgency of treatment, patient fears of actual or perceived side effects from medications and clinician confidence in prescribing, and costs to patients and limited funding for coordinated models of care.Common facilitators included engaging patients in self-management and in advocacy, developing pathways for care for different risk profiles and ensuring coordination of care between primary and tertiary care settings, and improving communication between clinicians. ConclusionsThese findings provide a foundation for the development of empirically-based implementation strategies tailored to the Australian healthcare context and highlight the importance of multi-level approaches to improving FH detection and management.Future work that is focussed on mapping strategies to these barriers and facilitators using implementation frameworks is needed to develop a national implementation plan for the integration of new guidance on the care of FH.