Association of multiple biomarkers, CRP, Uric acid, Urea, Ferritin with Metabolic Syndrome among young adults in Bhubaneswar

MetS is a conglomeration of several disorders namely unusual weight gain, insulin resistance, hypertension and dyslipidemia that are likely to increase the risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). The association of certain biomarkers namely serum CRP, uric acid, urea and ferritin levels collectively and its relationship with other components like fasting blood glucose and lipid profile among young adults and adults learning or employed in different academic organizations of Bhubaneswar were determined in this study. Screening for MetS was carried out as s per guidelines of the NPCDCS in India. Socio-demographic, physical and biochemical data were collected from the participants using structured questionnaires. Blood samples, 5 ml were obtained for various investigations such as blood glucose, lipid profile, serum C-reactive protein (CRP), uric acid, urea and ferritin. In our study, the risk factors for MetS, i.e., increased waist circumference, hypertension, physical inactivity, prolonged online activity, irregular sleep patterns, dyslipidemia (high triglycerides, low HDL) is higher in the young adults in the study. CRP, Uric acid and ferritin levels were higher in participants with Metabolic Syndrome. Screening young adults, for body mass index, waist circumference, lipid profile, blood glucose levels, blood pressure and biomarkers like CRP, Urea, Uric acid and Ferritin, at regular intervals, will help in detecting the vulnerable individuals. The need for shielding and control of chronic diseases among the young adults is emphasized in view of the higher prevalence of MetS.