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March 16, 2026˜The œJournal of invasive cardiology/˜The œjournal of invasive cardiology0 citations

Late Degeneration of a Transcatheter Aortic Valve Replacement Presenting With Flail Leaflet

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LALeila AlizadehMDMaria DrosouTOTakayuki Onishi

Key Result

An 80-year-old man developed dyspnea due to flail leaflet in a transcatheter aortic valve replacement nine years after implantation of a 29-mm Evolut R valve.

Key Points

  • To explore the late degeneration of a transcatheter aortic valve replacement in an elderly patient.
  • Case report detailing patient history including prior surgical interventions and valve replacement.
  • Clinical observation of symptoms such as dyspnea.
  • Follow-up evaluation after valve implantation.
  • Patient presented with dyspnea nine years post-transcatheter aortic valve replacement.
  • Identified complications related to late degeneration of the valve and flail leaflet.

Structured PICO

P
Population
1 80-year-old man presenting with dyspnea, with a history of aborted surgical aortic valve replacement due to extensive ascending aortic calcification.
I
Intervention
Transcatheter aortic valve replacement with a 29-mm Evolut R self-expanding valve 9 years prior
O
Outcome
Late valve degeneration presenting with flail leaflet

This case highlights the potential for late structural valve degeneration presenting as a flail leaflet 9 years after self-expanding transcatheter aortic valve replacement.

Abstract

An 80-year-old man presented with dyspnea. Nine years earlier, he had undergone transcatheter aortic valve replacement with a 29-mm Evolut R self-expanding valve (Medtronic) following aborted surgical aortic valve replacement due to extensive ascending aortic calcification.

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Cite This Study

Alizadeh et al. (2026) studied this question. An 80-year-old man developed dyspnea due to flail leaflet in a transcatheter aortic valve replacement nine years after implantation of a 29-mm Evolut R valve.

synapsesocial.com/papers/69b79d538166e15b153aac09https://doi.org/10.25270/jic/26.00064
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