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Systematic review highlights the impact of drugs on enamel development, suggesting caution in human applications.
This systematic review synthesizes experimental evidence on the biological vulnerability of developing enamel to pharmacological exposure, highlighting potential mechanisms underlying enamel thinning and hypomineralization while underscoring the need for cautious interpretation when extrapolating animal data to human clinical contexts. PROSPERO Registration No.: CRD42025606606.
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Zamri et al. (2026) studied this question.
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