Key result
Pediatric obesity is linked to depot-specific metabolic alterations, with 24 shifted metabolites in visceral fat.
Why the study?
What are the depot-specific metabolic differences between subcutaneous and visceral adipose tissue in pediatric obesity?
Observational (n=30)
What are the depot-specific metabolic differences between subcutaneous and visceral adipose tissue in pediatric obesity?
Visceral adipose tissue in pediatric obesity displays a metabolic profile consistent with heightened lipotoxicity and mitochondrial stress compared to subcutaneous adipose tissue.
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López-Gonzálvez et al. (2026) conducted an observational in Pediatric obesity (n=30). Overweight/obesity vs. Normal weight was evaluated on Significantly altered metabolites in visceral white adipose tissue (vWAT). Pediatric overweight and obesity was associated with pronounced depot-specific metabolic heterogeneity, with visceral adipose tissue exhibiting 24 significantly altered metabolites compared to controls.
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