Transparent UV‐Curable Self‐Sanitizing Coatings Applicable to Diverse Surfaces and High‐Touch Screens to Mitigate Deadly Pathogen Transmission

Contamination on high‐touch surfaces such as hospital equipment, kiosks, door handles, and elevator buttons presents a major risk for pathogen transmission. Antimicrobial coatings that preserve surface performance while rapidly inactivating pathogens are therefore in high demand. We developed a transparent poly(alkyl imidazolium chloride) coating that combines strong electrostatic interactions of the cationic moiety with optimized alkyl‐chain–driven membrane disruption, generating durable self‐sanitizing surfaces. The coatings were synthesized, spray‐applied, and UV‐cured using a substrate‐independent process, enabling application to stainless steel, plastics, glass, and non‐woven fabrics without compromising performance. Designed for practical use, the coatings demonstrated broad antimicrobial activity, contact‐based deactivation across diverse pathogens, and stability under varying humidity and long‐term storage. Excellent optical transmission and durability make them particularly suited for transparent touchscreens, where clarity and responsiveness must be preserved. Tests further confirmed effective inhibition of airborne viruses and biofilm formation. Among the variants, the C6‐alkyl chain coating exhibited the highest efficacy, achieving rapid pathogen inactivation through balanced amphiphilicity that enhances electrostatic binding and hydrophobic bilayer insertion. This scalable, durable, and transparent antimicrobial coating offers a practical solution for mitigating pathogen spread on interactive surfaces, reducing reliance on manual disinfection, and lowering public health and economic burdens during pandemics.