Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 16, 2026The Indian Journal of Medical ResearchOpen Access

Experiences from inborn errors of immunity registry of India: A preliminary report

View Full Paper
Ask AI
Bookmark
Share

Authors

RYReetika Malik YadavDSDeepti SuriPost Graduate Institute of Medical Education and ResearchSSSatinderpal SinghPost Graduate Institute of Medical Education and Research

Discussion

Loading...

Member takes

Implication

This registry assesses disease burden and treatment outcomes in congenital immune disorders, indicating a need for better data and care.

Key Points

  • The study aims to establish a registry for inborn errors of immunity in India to understand their prevalence and improve patient care.
  • Developed a registry under ICMR with participating centres across India.
  • Collected data in a structured format after ethics approval from centres.
  • Included cases with molecular confirmation or defined as per European Society for Immunodeficiencies.
  • Compiled and analyzed data using Epi Info v7.2.5.0.
  • Enrolled 676 patients from six centres between 2019 and 2024.
  • Identified common immunodeficiencies: CID (27.6%), antibody deficiency (21.6%), and phagocyte defects (17.3%).
  • Median age of presentation was 16 months with an average diagnostic delay of 16 months.
  • Recurrent infections were the most common clinical manifestation (67.9%).
  • 70% of patients with antibody deficiency received IVIG, and 17.4% died from infections by 2024.

Cite This Study

Yadav et al. (2026) studied this question.

synapsesocial.com/papers/69b79e6e8166e15b153abccdhttps://doi.org/10.25259/ijmr_1850_2025
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Assessment of the first presentations of common variable immunodeficiency in a large cohort of patients2023 · 10 citations
  2. 2The Primary Immunodeficiency Database in Japan2022 · 16 citations
  3. 3The European internet-based patient and research database for primary immunodeficiencies: results 2004–062007 · 128 citations
  4. 4Global systematic review of primary immunodeficiency registries2020 · 147 citations
  5. 5Newborn Screening for Primary Immunodeficiencies: The Gaps, Challenges, and Outlook for Developing Countries2020 · 31 citations