What question did this study set out to answer?

The study aims to establish a registry for inborn errors of immunity in India to understand their prevalence and improve patient care.

Experiences from inborn errors of immunity registry of India: A preliminary report

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This registry assesses disease burden and treatment outcomes in congenital immune disorders, indicating a need for better data and care.

The study aims to establish a registry for inborn errors of immunity in India to understand their prevalence and improve patient care.
Developed a registry under ICMR with participating centres across India.
Collected data in a structured format after ethics approval from centres.
Included cases with molecular confirmation or defined as per European Society for Immunodeficiencies.
Compiled and analyzed data using Epi Info v7.2.5.0.
Enrolled 676 patients from six centres between 2019 and 2024.
Identified common immunodeficiencies: CID (27.6%), antibody deficiency (21.6%), and phagocyte defects (17.3%).
Median age of presentation was 16 months with an average diagnostic delay of 16 months.
Recurrent infections were the most common clinical manifestation (67.9%).
70% of patients with antibody deficiency received IVIG, and 17.4% died from infections by 2024.

Yadav et al. (2026) studied this question.

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View Full Paper

Ask AI

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Authors

This registry assesses disease burden and treatment outcomes in congenital immune disorders, indicating a need for better data and care.

The study aims to establish a registry for inborn errors of immunity in India to understand their prevalence and improve patient care.
Developed a registry under ICMR with participating centres across India.
Collected data in a structured format after ethics approval from centres.
Included cases with molecular confirmation or defined as per European Society for Immunodeficiencies.
Compiled and analyzed data using Epi Info v7.2.5.0.
Enrolled 676 patients from six centres between 2019 and 2024.
Identified common immunodeficiencies: CID (27.6%), antibody deficiency (21.6%), and phagocyte defects (17.3%).
Median age of presentation was 16 months with an average diagnostic delay of 16 months.
Recurrent infections were the most common clinical manifestation (67.9%).
70% of patients with antibody deficiency received IVIG, and 17.4% died from infections by 2024.

Yadav et al. (2026) studied this question.

View Full Paper

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