Evaluation shows negligible HIV-1 drug-resistance impact on antiretroviral susceptibility in Italy, indicating an area of focus for health strategies.
A high proportion of HIV-1 non-B subtypes circulate in Italy. TDR prevalence is around 12% using NGS at Sanger-like threshold and moderately increases to 15% when NGS is set at 10%. However, the impact of the detected TDR on the susceptibility to currently used antiretrovirals in clinical practice is negligible.
No takes yet. Share an insight, caveat, or question.
Armenia et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: