Pan-immune-inflammation value and systemic inflammation indices as predictors of disease severity in hidradenitis suppurativa

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Key Points

The study aims to evaluate specific inflammatory indices as predictors of disease severity in hidradenitis suppurativa patients.
Conducted a retrospective analysis of hidradenitis suppurativa patients and controls.
Reviewed demographic data, laboratory results, and clinical severity scores.
Calculated PIV, SII, and SIRI from blood counts of neutrophils, lymphocytes, monocytes, and platelets.
Utilized group comparisons, correlation analyses, ROC curves, and logistic regression models.
101 hidradenitis suppurativa patients showed higher inflammatory activity compared to 82 controls.
Neutrophils were significantly increased in HS patients (average of 5.88 vs 4.12×10³/mm³).
PIV, SII, and SIRI showed correlation with disease severity measures (Hurley stage and IHS4).

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Retrospective analysis evaluates inflammatory indices in hidradenitis suppurativa, suggesting their role in severity diagnosis.

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Kurmuş et al. (2026) studied this question.

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