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To introduce and evaluate Minimap2, a versatile sequence alignment program designed for mapping and aligning nucleotide sequences.

May 4, 2018BioinformaticsOpen Access

Minimap2: pairwise alignment for nucleotide sequences

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To introduce and evaluate Minimap2, a versatile sequence alignment program designed for mapping and aligning nucleotide sequences.
Designed an optimized algorithm for pairwise alignment across diverse genomic and transcriptomic nucleotide data.
Implemented indexing, seeding, and chaining strategies to efficiently process long and short sequencing reads against reference genomes.
Provides rapid, accurate pairwise alignment across diverse nucleotide sequencing datasets.
Enables versatile mapping performance for both long-read and short-read genomic sequencing workflows.

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Computational analysis demonstrates pairwise alignment across nucleotide sequences, facilitating rapid and accurate genomic mapping.

Supplementary data are available at Bioinformatics online.

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Heng Li (2018) studied this question.

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Computational analysis demonstrates pairwise alignment across nucleotide sequences, facilitating rapid and accurate genomic mapping.

Supplementary data are available at Bioinformatics online.