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March 17, 2026Ecotoxicology and Environmental SafetyOpen Access

Role of humic acid in modulating the combined toxicity of polylactic acid microplastics and diflubenzuron: Impacts on mitochondrial genotoxicity in Daphnia magna

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Authors

GKGunay KarimovaHKHanseong KimKKKimleng Keang

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Overview

Investigates the impacts of humic acid on toxicity from microplastics and pesticide in Daphnia magna, suggesting natural factors alter risk assessments.

Key Points

  • The aim is to explore how humic acid influences the toxicity of polylactic acid microplastics and diflubenzuron in aquatic environments.
  • Conducted acute 48-hour exposure tests on Daphnia magna.
  • Measured mortality and sublethal effects like oxidative stress biomarkers and mitochondrial DNA.
  • Examined how humic acid interacts with PLA microplastics and diflubenzuron.
  • Humic acid reduced the acute toxicity from the combination of PLA microplastics and diflubenzuron.
  • The high concentration of diflubenzuron decreased mitochondrial DNA copy number.
  • Compensatory mechanisms increased ATP content in Daphnia magna under combined exposure.

Cite This Study

Karimova et al. (2026) studied this question.

synapsesocial.com/papers/69b8ef12deb47d591b8c52a4https://doi.org/10.1016/j.ecoenv.2026.120020
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