Pulse Entdecken nav.journalClub Debatten Trends Forschende Zeitschriften

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Start Entdecken nav.journalClub Trends

⌘+K

Identification and Characterisation of a New Null Allele: HLA‐A*03:528N | Synapse

March 17, 2026

View Full Paper

Identification and Characterisation of a New Null Allele: HLA‐A*03:528N

LLLucia Assunta LongaAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo LPL. PerottiAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo MPMaristella PruccaAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo

Key Points

This research aims to identify and characterize the new null allele HLA-A*03:528N and its genetic implications.
Analysis of genetic sequences
Identification of nucleotide duplications
Characterization of allele functions
HLA-A*03:528N shows a 4-nucleotide duplication in exon 1
The duplication leads to a frameshift mutation
A stop codon is generated in exon 2, likely affecting protein function

Abstract

ABSTRACT HLA‐A*03:528N has a 4‐nucleotide duplication in exon 1 that generates a frameshift with a stop codon in exon 2.

KI fragen

Like

Bookmark

Share

View Full Paper

Cite This Study

Longa et al. (Sun,) studied this question.

synapsesocial.com/papers/69b8f0fddeb47d591b8c5b0a https://doi.org/https://doi.org/10.1111/tan.70663

KI fragen

Like

Bookmark

Share

View Full Paper