Key result
Anatomical repair for ccTGA shows comparable 20-year survival to physiological repair.
Why the study?
The optimal surgical strategy for congenitally corrected transposition of the great arteries remains debated.
Does anatomical repair improve long-term outcomes compared to physiological repair in patients with congenitally corrected transposition of the great arteries?
Cohort (n=107)
No
Does anatomical repair improve long-term outcomes compared to physiological repair in patients with congenitally corrected transposition of the great arteries?
Absolute Event Rate: 79% vs 82%
p-value: p=0.97
While overall survival is comparable between anatomical and physiological repair for ccTGA, atrial switch with arterial switch (AR-A) yields the most favorable long-term functional outcomes and should be the preferred strategy when feasible.
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AR-A should be preferred when feasible in ccTGA; extends evidence for selective anatomical repair.
Tominaga et al. (2026) conducted a cohort in Congenitally corrected transposition of the great arteries (ccTGA) (n=107). Anatomical repair vs. Physiological repair was evaluated on All-cause mortality (reported as 20-year survival) (p=0.97). Anatomical repair for congenitally corrected transposition of the great arteries showed comparable 20-year survival to physiological repair (79% vs 82%, p=0.97).
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