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March 17, 2026Apollo MedicineOpen Access

Clinical Profile, Laboratory Parameters and Comorbid Associations in Non-alcoholic Fatty Liver Disease

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Prospective observational study evaluates fibrosis and metabolic comorbidities in NAFLD patients, indicating significant health risks.

This study aims to assess the clinical profile, laboratory parameters, and comorbid associations in patients with NAFLD.
Conducted a prospective observational study over 12 months.
Enrolled 115 adult patients diagnosed with NAFLD via ultrasonography.
Recorded clinical features, biochemical parameters, and metabolic comorbidities.
Performed non-invasive fibrosis assessment using FIB-4, APRI, and NAFLD Fibrosis Score.
Applied statistical analysis using SPSS version 25.
Mean age of patients was 61.7 years with a slight female predominance.
Metabolic syndrome and diabetes mellitus were the most common comorbidities.
Over 70% of patients had high or advanced fibrosis identified by FIB-4.
Advanced fibrosis was prevalent in patients aged ≥60 years.
Portal hypertension and ascites were the most common complications.

Bharadwaj et al. (2026) studied this question.

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