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Pulmonary manifestations in adult patients with chronic granulomatous disease

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This study aims to analyze pulmonary manifestations in adult patients with chronic granulomatous disease.
Retrospective analysis of medical records for 52 adult patients with CGD in the French National database.
Examined pulmonary infection and inflammatory events before and after the age of 16.
Evaluated the frequency of respiratory infections and the need for immunosuppressive treatment.
Patients showed 49 pulmonary infections and 9 inflammatory events before age 16.
Post-age 16, 45 infections were recorded, including 23 invasive aspergillosis and 22 bacterial infections.
Aspergillosis was often asymptomatic, with 14 patients showing no symptoms.
Biopsies mostly revealed granulomas, and 18 respiratory inflammatory events were noted, often requiring immunosuppressive drugs.

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Retrospective analysis examines pulmonary manifestations in adults with chronic granulomatous disease, suggesting a need for focused care.

Salvator et al. (2013) studied this question.

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Retrospective analysis examines pulmonary manifestations in adults with chronic granulomatous disease, suggesting a need for focused care.