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March 18, 2026Journal of Drug Delivery and TherapeuticsOpen Access

Innovative Nanocarrier Strategies for Enhanced Docetaxel Delivery in Cancer Therapy

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Authors

OKOmkar KolheMarathwada Agricultural UniversityMRMukesh RatnaparkhiMarathwada Agricultural University

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Implication

This review explores how nanocarrier systems improve docetaxel effectiveness in cancer treatment, suggesting potential for broader clinical application.

Key Points

  • To review novel nanocarrier formulations for enhancing docetaxel delivery in cancer therapy while addressing existing limitations.
  • Reviewed various nanocarrier formulations for docetaxel
  • Analyzed in-vitro and in-vivo evaluations across cancer types
  • Discussed challenges such as stability and quality control of nanoformulations
  • Nanocarriers significantly enhance the solubility and effectiveness of docetaxel
  • Evidence of improved bio-distribution in tumor cells due to the EPR effect
  • Challenges remain in the clinical application of nanoformulations including stability and regulatory concerns

Cite This Study

Kolhe et al. (2026) studied this question.

synapsesocial.com/papers/69ba420a4e9516ffd37a1e47https://doi.org/10.22270/jddt.v16i3.7601
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Also Consider

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  1. 1Safety and Efficacy of BIND-014, a Docetaxel Nanoparticle Targeting Prostate-Specific Membrane Antigen for Patients With Metastatic Castration-Resistant Prostate Cancer2018 · 273 citations
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  3. 3Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells2017 · 46 citations
  4. 4Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity2016 · 108 citations