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March 19, 2026Cancer Management and ResearchOpen Access

Preoperative Prognostic Nutritional Index Predicts Postoperative Outcomes in Colorectal Cancer: A Propensity Score-Matched Cohort Study

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Authors

CKChew-Teng KorNational Chung Hsing University TTTsung-Jung TsaiChanghua Christian Hospital TCTsung ChuangChanghua Christian Hospital

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Implication

This cohort study evaluates preoperative PNI to predict postoperative complications and survival in colorectal cancer, suggesting its role in risk stratification.

Key Points

This research aims to determine whether preoperative PNI can predict postoperative complications and survival rates in colorectal cancer patients undergoing surgery.
Retrospective review of records for 2,026 colorectal cancer patients who underwent surgery.
Stratification of patients into high and low PNI groups through propensity score matching.
Assessment of in-hospital complications, 5-year overall survival, and disease-free survival.
Application of multivariable logistic regression and Cox proportional hazards models for analysis.
High PNI correlates with significantly lower overall complication rates (adjusted odds ratio [aOR] = 0.22).
High PNI is significantly associated with improved 5-year overall survival (aHR = 0.45), but not disease-free survival.
High PNI remains protective against both cancer-related and non-cancer-related mortality in additional analyses.

Cite This Study

Kor et al. (2026) studied this question.

synapsesocial.com/papers/69bb91c7496e729e6297f2bf https://doi.org/10.2147/cmar.s558639

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Implication

This cohort study evaluates preoperative PNI to predict postoperative complications and survival in colorectal cancer, suggesting its role in risk stratification.

Preoperative Prognostic Nutritional Index Predicts Postoperative Outcomes in Colorectal Cancer: A Propensity Score-Matched Cohort Study

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Implication

Key Points

Cite This Study

Preoperative Prognostic Nutritional Index Predicts Postoperative Outcomes in Colorectal Cancer: A Propensity Score-Matched Cohort Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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