What question did this study set out to answer?

To emphasize the challenges in diagnosing Wernicke encephalopathy (WE) and the effectiveness of high-dose thiamine treatment.

March 19, 2026CureusOpen Access

Psychiatric-Predominant Wernicke Encephalopathy With Normal Blood Thiamine Levels: A Case Report

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Authors

SIShota InadaFukushima Medical University YMYuhei MoriFukushima Medical University SKShin KumashiroTaoka Hospital

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Implication

Case report discusses treatment effectiveness of high-dose thiamine in a psychiatric patient with Wernicke Encephalopathy, highlighting complex diagnoses.

Key Points

To emphasize the challenges in diagnosing Wernicke encephalopathy (WE) and the effectiveness of high-dose thiamine treatment.
Descriptive case report of a 56-year-old woman with a history of chronic alcohol use and psychiatric hospitalization
Neurological examination and brain CT scans were conducted
Laboratory tests, including normal blood thiamine levels, were performed
High-dose intravenous thiamine treatment was administered over five days
Patient showed rapid improvement in psychiatric symptoms and cognitive function after thiamine treatment
HDS-R score increased from 1 to 27 by day 17
Wernicke encephalopathy was diagnosed after clinical improvement and atypical presentation
Diagnosis of WE was challenging due to normal blood thiamine levels

Cite This Study

Inada et al. (2026) studied this question.

synapsesocial.com/papers/69bb9247496e729e6297f6df https://doi.org/10.7759/cureus.105343

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Implication

Case report discusses treatment effectiveness of high-dose thiamine in a psychiatric patient with Wernicke Encephalopathy, highlighting complex diagnoses.

Psychiatric-Predominant Wernicke Encephalopathy With Normal Blood Thiamine Levels: A Case Report

Discussion

Member takes

Implication

Key Points

Cite This Study

Psychiatric-Predominant Wernicke Encephalopathy With Normal Blood Thiamine Levels: A Case Report

Discussion

Member takes

Implication

Key Points

Cite This Study

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