Ciprofloxacin–polymer conjugates targeted with iron( iii ) for effective treatment of intracellular bacterial infections

Key Points

• This research aims to develop ciprofloxacin-polymer conjugates that can effectively target and treat intracellular bacterial infections.
• Creation of ciprofloxacin-polymer conjugates
• In vitro testing against intracellular bacteria
• Assessment of targeting efficiency using iron(III)
• Demonstrated enhanced effectiveness against multidrug-resistant bacteria
• Increased bacterial cell penetration compared to standard antibiotics
• Potential for reduced side effects due to targeted delivery