445eP Tumor-infiltrating lymphocytes and blood-based immune parameters are differentially associated with brain metastases and survival in small cell lung cancer

Key Points

• This research aims to clarify how tumor and blood immune factors relate to brain metastases and survival in small cell lung cancer.
• Analyzed tumor-infiltrating lymphocytes in small cell lung cancer samples.
• Assessed blood-based immune parameters in patients.
• Evaluated associations with brain metastases and overall survival.
• Higher tumor-infiltrating lymphocytes correlate with improved survival.
• Specific blood immune parameters show varied relationships with brain metastases.
• The study highlights the role of immune factors in tumor microenvironment and prognosis.