240P Molecular drivers and temporal patterns of recurrence after R0 in non-small cell lung cancer: EGFR- and ALK-specific insights from the GECP thoracic tumour registry

Key Points

• The study aims to examine how molecular alterations affect recurrence patterns and survival after complete resection in non-small cell lung cancer.
• Characterized recurrence patterns among patients with EGFR mutations and ALK rearrangements.
• Analyzed recurrence-free survival (RFS) data from a thoracic tumour registry.
• Identified temporal patterns of recurrence after R0 resection.
• Patients with EGFR mutations showed distinct recurrence patterns compared to ALK-rearranged tumors.
• Recurrence-free survival varied significantly between the two molecular subtypes.
• Timing of recurrence was influenced by specific molecular alterations.