This analysis identifies KL-6 and CRP as predictive markers for progressive pulmonary fibrosis in systemic sclerosis-associated interstitial lung disease, suggesting their clinical relevance.
Baseline KL-6 and CRP values identify distinct subsets of SSc-ILD patients. Elevated baseline KL-6 levels and a significant rise over the subsequent six months are associated with an increased risk of PPF, supporting their potential as prognostic biomarkers.
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Yomono et al. (2026) studied this question.
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