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March 19, 2026HLA2 citations

The Novel HLA‐DRB1*12:01:14 Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual

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XTXiangfeng TangYSYing‐Jian SiWCWei Chen

Key Points

  • To identify and characterize the novel HLA-DRB1*12:01:14 allele in a specific individual.
  • Utilized Sanger dideoxy nucleotide sequencing to analyze genetic material.
  • Focused on detecting changes in the HLA-DRB1 gene, particularly exon 5.
  • Discovered the HLA-DRB1*12:01:14 allele with a single synonymous nucleotide change from HLA-DRB1*12:01:01:01.

Abstract

The HLA-DRB1*12:01:14 allele differs from HLA-DRB1*12:01:01:01 by a single synonymous nucleotide change in exon 5.

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Cite This Study

Tang et al. (2026) studied this question.

synapsesocial.com/papers/69bb92f2496e729e62980a3bhttps://doi.org/10.1111/tan.70619
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