What question did this study set out to answer?

To determine the minimal clinically important difference and substantial clinical benefit for the Mayo Wrist Score after carpal tunnel release and contextualize QuickDASH changes.

March 19, 2026CureusOpen Access

Minimal Clinically Important Difference and Substantial Clinical Benefit After Carpal Tunnel Release Using the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) and Mayo Wrist Scores: A Prospective Observational Study

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Authors

ABAmmar Al BalushiOman Medical College ALAbdullah Al LawatiSultan Qaboos Hospital MSMoath ShummoSultan Qaboos University Hospital

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Implication

Observational study reveals clinically important thresholds for outcomes in patients after carpal tunnel release, suggesting meaningful improvement.

Key Points

To determine the minimal clinically important difference and substantial clinical benefit for the Mayo Wrist Score after carpal tunnel release and contextualize QuickDASH changes.
Prospective observational study design
Inclusion of adult patients undergoing isolated carpal tunnel release
Assessment of QuickDASH and Mayo Wrist Scores preoperatively and at six-month follow-up
Calculation of MCID and SCB using anchor-based and distribution-based methods
Receiver operating characteristic curve analysis for Mayo Wrist Score
92 patients enrolled; 73 completed the six-month follow-up.
Anchor-based MCID for Mayo Wrist Score was 11.5 points (AUC = 0.77).
SCB threshold for Mayo Wrist Score was 13.5 points (AUC = 0.91).
Significant postoperative improvements noted in both QuickDASH and Mayo Wrist Scores.

Cite This Study

Balushi et al. (2026) studied this question.

synapsesocial.com/papers/69bb9300496e729e62980c7b https://doi.org/10.7759/cureus.105359

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Implication

Observational study reveals clinically important thresholds for outcomes in patients after carpal tunnel release, suggesting meaningful improvement.

Minimal Clinically Important Difference and Substantial Clinical Benefit After Carpal Tunnel Release Using the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) and Mayo Wrist Scores: A Prospective Observational Study

Discussion

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Implication

Key Points

Cite This Study

Minimal Clinically Important Difference and Substantial Clinical Benefit After Carpal Tunnel Release Using the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) and Mayo Wrist Scores: A Prospective Observational Study

Discussion

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Implication

Key Points

Cite This Study

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