Developing and validating models to predict overall survival in non-surgical prostate cancer patients with bone metastases, suggesting early treatment shifts.
The EST model effectively assesses OS in nonsurgical PCBM. The Gleason score holds greater prognostic value than local anatomical staging in this cohort, suggesting clinicians should prioritize early, aggressive combination treatments for high-Gleason, high-burden patients.
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Yang et al. (2026) studied this question.
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