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This review aims to explore the epigenetic mechanisms by which BPA affects reproductive health and its transgenerational implications.

March 19, 2026Current ZoologyOpen Access

Transgenerational Reproductive Risks of BPA: Epigenetic Mechanisms and Biomarker Applications. A Critical Review

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This review discusses BPA's effects on male reproductive health, indicating significant epigenetic consequences for future generations.

This review aims to explore the epigenetic mechanisms by which BPA affects reproductive health and its transgenerational implications.
Critical review of existing literature on BPA's reproductive effects and epigenetic mechanisms.
Analysis of BPA-induced changes in spermatogenesis and hormone signaling.
Discussion of therapeutic interventions and regulatory implications.
BPA exposure leads to impaired sperm quality and spermatogenesis in affected individuals.
Epigenetic changes in sperm, such as DNA methylation, result in fertility defects in future generations.
Therapeutic methods are being investigated to mitigate BPA's reproductive impact.

Okon et al. (2026) studied this question.

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