Kidney injury molecule-1 (KIM-1) as a biomarker for detection of subclinical nephrotoxic effect of chronic organophosphorus exposure | Synapse
March 19, 2026
Kidney injury molecule-1 (KIM-1) as a biomarker for detection of subclinical nephrotoxic effect of chronic organophosphorus exposure
Key Points
This research aims to assess the role of KIM-1 in detecting renal injury due to chronic exposure to organophosphorus compounds.
Evaluated the impact of chronic organophosphorus exposure on renal health
Monitored KIM-1 levels in relation to kidney function
Assessed subclinical tubular injury indicators based on KIM-1
Analyzed data to determine the sensitivity of KIM-1 as a biomarker.
KIM-1 levels significantly increase with chronic organophosphorus exposure
Indication of early renal damage even in subclinical stages
KIM-1 is effective in monitoring tubular injury during long-term exposure.
Abstract
Chronic OP exposure may cause progressive renal damage. KIM-1 is a sensitive biomarker for early detection and monitoring of subclinical tubular injury.