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March 19, 2026Chemical Science2 citationsOpen Access

Silver-Catalysed Intermolecular Benzylic-Selective C–H Amidation via Nitrene Transfer

SPSubir PanjaTTTuấn Anh TrịnhEWEthan M. Warrington

Key Points

  • To explore the use of silver as a catalyst for intermolecular benzylic-selective C–H amidation via nitrene transfer.
  • Implemented metal-catalyzed C–H functionalization techniques
  • Utilized silver as a catalyst for nitrene transfer
  • Evaluated selectivity and efficiency in amidation reactions
  • Successfully achieved selective C–H amidation in benzylic positions
  • Demonstrated potential for upgrading simple hydrocarbons
  • Highlighted versatility for synthetic building block creation.

Abstract

Transition metal-catalyzed C-H functionalization is a powerful strategy to upgrade simple hydrocarbons to versatile synthetic building blocks and is a useful tool for the late-stage functionalization of complex molecules. In...

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Cite This Study

Panja et al. (2026) studied this question.

synapsesocial.com/papers/69bb9357496e729e629815b7https://doi.org/10.1039/d5sc10184k
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