Electroacupuncture mitigates lung injury, increases endogenous antioxidant levels and modulates Nrf2 signaling in a rat model of chronic obstructive pulmonary disease

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Key Points

This research aims to explore the effects of electroacupuncture on lung injury and antioxidant levels in a rat model of chronic obstructive pulmonary disease (COPD).
Utilized a rat model to simulate COPD conditions.
Administered electroacupuncture treatment.
Assessed levels of antioxidants and Nrf2 signaling pathways.
Evaluated the degree of lung injury.
Electroacupuncture treatment significantly reduced lung injury.
Increased endogenous antioxidant levels were observed.
Nrf2 signaling pathways were modulated in favor of antioxidant effects.

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Animal study demonstrates electroacupuncture reduces lung injury in COPD, suggesting new treatment options.

EA was beneficial for the treatment of COPD in this rat model and exerted antioxidant effects via mechanisms potentially related to Nrf2 signaling.

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Tian et al. (2026) studied this question.

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