HIV Pre-Exposure Prophylaxis Awareness among Individuals in Treatment for Opioid Use Disorder in the United States: A Cross-Sectional Study

This study examined PrEP awareness among HIV-negative individuals in treatment for opioid use disorder (OUD; n = 179), and associations with demographic characteristics, sexual and injection behaviors, and treatment modalities. Overall, 48% of participants reported PrEP awareness. Bivariate logistic regression showed that, compared to others, individuals who were older, African American/Black, and in methadone treatment less frequently reported PrEP awareness ( p ≤.018), while those who reported sex with a person who injects drugs, inpatient/day treatment, and self-help group attendance more frequently reported PrEP awareness ( p ≤.041). Increased education and outreach to PrEP eligible individuals in methadone and other opioid treatment programs appears warranted.