What does this research mean for the field?

A customized version of the Simplified Acute Physiology Score 3 (SAPS 3-Custom) demonstrates valid prognostic performance compared to the standard equation in contemporary Brazilian and Uruguayan intensive care unit patients. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to compare the effectiveness of the standard SAPS 3 score with a customized version in intensive care unit patients.

March 21, 2026Critical Care Science1 citations

Contemporary validation of a SAPS 3 customized version in patients admitted to Brazilian and Uruguayan intensive care units: a multicenter cohort study

MSMarcio SoaresD’Or Institute for Research and Education LBLunna Perdigão BorgesTa Solutions (China)GBGastón BurghiHospital Maciel

Key Points

This research aims to compare the effectiveness of the standard SAPS 3 score with a customized version in intensive care unit patients.
Conducted a retrospective cohort study
Included 262,198 adults
Data collected from 177 intensive care units in Brazil and Uruguay
The customized SAPS 3 version outperformed the standard version in predictive accuracy
Key clinical outcomes were identified for improved patient assessment

Abstract

Objective: To compare the performance of the standard equation (SAPS 3-SE) and a customized version (SAPS 3-Custom) of the Simplified Acute Physiology Score 3 in a contemporary cohort of Brazilian and Uruguayan intensive care unit patients. Methods: We conducted a retrospective cohort study of 262,198 adults admitted to 177 intensive care units between 2022 …

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