Granulomatosis With Polyangiitis Presenting With Initially Isolated Cutaneous Facial Ulceration Without Early Other Characteristic Changes

Granulomatosis with polyangiitis (GPA) is a multiorgan system disease process in which cutaneous involvement is not uncommon. However, this article reports a case of GPA that presented with an unusually destructive chronic cutaneous facial lesion without other characteristic organ changes to suggest GPA, which represented a unique diagnostic challenge. It highlights the importance of maintaining high suspicion for vasculitic disease processes and prompt diagnosis to reduce disease burden.