What question did this study set out to answer?

The aim is to develop a wearable sensor for real-time detection of chloride ions in sweat.

March 21, 2026Electrochimica ActaOpen Access

Wearable paper-based potentiometric sensor for real-time detection of chloride ions in sweat

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This work demonstrates a novel wearable sensor for monitoring chloride ions in sweat, suggesting advancements in non-invasive diagnostics.

The aim is to develop a wearable sensor for real-time detection of chloride ions in sweat.
Developed a potentiometric sensor using office paper and microfluidic architecture.
Integrated chloride-selective membranes for ion sensing.
Conducted hysteresis studies to confirm minimal memory effects.
Tested sensitivity and detection limits against reference titration methods.
Achieved a sensitivity of 56 mV/log aCl⁻.
Demonstrated a linear detection range of 1–200 mmol L⁻¹.
Established a detection limit of 74 µmol L⁻¹.
Bias values compared to reference methods ranged from −14% to +4%.

Fiore et al. (2026) studied this question.

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This work demonstrates a novel wearable sensor for monitoring chloride ions in sweat, suggesting advancements in non-invasive diagnostics.