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Synapse
March 21, 2026Intensive Care Medicine2 citationsOpen Access

Predictive factors of successful renal replacement therapy weaning

KCKhalil ChaïbiYAYanis AkrourGLGuillaume Louis

Key Points

  • The research aims to identify predictive factors for successfully weaning patients off renal replacement therapy (RRT).
  • Analyzed a conservative RRT initiation cohort.
  • Validated the tool in a diverse ICU population.
  • Developed a bedside tool for estimating discontinuation probability.
  • The bedside tool effectively predicts sustained RRT discontinuation.
  • Validation showed high accuracy across different ICU settings.

Abstract

The UNDERSCORE, derived from a homogeneous conservative RRT initiation cohort and validated in a diverse ICU population, provides a bedside tool to estimate the probability of sustained RRT discontinuation after an initial clinician-initiated stop.

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Cite This Study

Chaïbi et al. (2026) studied this question.

synapsesocial.com/papers/69be34f26e48c4981c6730b8https://doi.org/10.1007/s00134-026-08357-x
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