⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

March 17, 2026ESMO OpenOpen Access

524P Bridging the gap between genomic profiling and targeted treatment in non-small cell lung cancer: A real-world NGS study

J. Jimenez Elbaile S. Esteras Per S. Navarro A. Romero Monleon K.A. Osorio M. Arribas Velasco C. Fernández Simón C. Gracia Cantero A. Moratiel Pellitero E. Quilez Bielsa M. Cruellas Lapena E. Arevalo Vazquez María Pilar Arruebo S. Menao M.D. Isla Casado MJ Cardiel R. Lastra del Prado

View Full Paper

Ask AI

Bookmark

Share

Key Points

To examine the role of STAS in predicting outcomes in non-small cell lung cancer patients undergoing surgery.
Analyzed data from 252 patients with non-small cell lung cancer
Classified tumors based on the 8th TNM system
Compared overall survival and disease-free survival between STAS-positive and STAS-negative groups
STAS was present in 58.8% of cases, showing significant association with worse overall survival
Patients with STAS positivity had a 50% mortality rate after sublobar resection
Notably higher incidence of lymph node metastasis in STAS-positive patients

Implication

This real-world NGS study identifies STAS as a key prognostic factor in lung cancer outcomes, suggesting new treatment considerations.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Elbaile et al. (2026) studied this question.

synapsesocial.com/papers/69be35166e48c4981c673333 https://doi.org/10.1016/j.esmoop.2026.106839

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1526P Integrin beta-6 (IB6) in focus: Contemporary real-world evidence on prevalence in non-small cell lung cancer (NSCLC)Original Research · 2026
2Spread through air spaces as an independent prognostic factor in resected lung adenocarcinoma: the role of resection typeOriginal Research · 2026
3Impact of STAS on Lung Resections for Adenocarcinoma: A Retrospective AnalysisCohort Study · 2026 · 2 citations
4The impact of STAS on recurrence-free and overall survival in T1-2N0 adenocarcinomas: a single-center retrospective studyCohort Study · 2026
5Spread through air spaces as a prognostic factor in resected non-small cell lung cancer2025