Obinutuzumab for membranous nephropathy: a systematic review using pooled case-level extraction analysis

Key Points

• The research aims to evaluate the effectiveness of obinutuzumab in achieving remission in membranous nephropathy.
• Conducted a systematic review and pooled analysis of case-level data
• Focused on PLA2R-associated membranous nephropathy
• Assessed clinical remission rates and contributing factors
• High clinical remission rates were observed for obinutuzumab in treatment of membranous nephropathy
• Remission rates may vary based on previous treatment responses
• Duration of follow-up plays a role in remission outcomes