Theoretical Verification of Coil-Array-Based 3D Magnetic Particle Imaging Technology

To enable real-time three-dimensional (3D) magnetic particle imaging (MPI) based on the field-free line (FFL), we propose a novel 3D MPI strategy that employs tomographic encoding through the spatially specific sensitivities of a receive coil array. Based on the spatially specific sensitivity encoding (SSSE) principle of the multi-channel receive coil array, 3D reconstruction can be achieved with only a 2D translational scan of the magnetic FFL. This approach reduces the scanning dimensionality by one compared to conventional parallel-beam tomography, offering a new paradigm for rapid, real-time 3D imaging. During reconstruction, multi-channel projection images transform the 3D inverse problem into a series of 1D inverse problems, significantly reducing computational complexity. Finally, the feasibility of sensitivity?based spatial encoding was validated in simulation experiments, demonstrating its broad application prospects and innovative value for 3D MPI imaging.