What question did this study set out to answer?

This research aims to investigate how age affects levels of natural moisturizing factor and caspase-14 in pediatric atopic dermatitis.

March 21, 2026Journal of the European Academy of Dermatology and Venereology0 citationsOpen Access

Age‐dependent reductions in natural moisturizing factor and caspase‐14 in paediatric atopic dermatitis

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RFR. FukudaNational Center For Child Health and Development KPKyongsun PakNational Center For Child Health and Development HYHazuki YasudaNational Center For Child Health and Development

Key Points

This research aims to investigate how age affects levels of natural moisturizing factor and caspase-14 in pediatric atopic dermatitis.
Analyzed skin samples from pediatric individuals with atopic dermatitis.
Measured levels of natural moisturizing factor and caspase-14 in the samples.
Assessed age as a variable in the expression of these biomarkers.
Natural moisturizing factor levels decrease with increasing age.
Caspase-14 levels also show age-dependent reductions.
Findings suggest a potential link between age and skin barrier function in atopic dermatitis.

Abstract

The data that support the findings of this study will be made available upon request. The data are not publicly available due to privacy or ethical restrictions.

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Age‐dependent reductions in natural moisturizing factor and caspase‐14 in paediatric atopic dermatitis

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Abstract

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