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March 12, 2026Journal of Health Sciences and MedicineOpen Access

Derived neutrophil-to-lymphocyte ratio as a predictor of negative appendectomy in acute appendicitis

Zeki Ogut Onur Ağ Bekir Sarıcık Adem Tunçer Nizamettin Kutluer Ayşe Azak Bozan Savaş Özer Tamer Gündoğdu Mehmet Buğra Bozan

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Key Points

This research examines how the derived neutrophil-to-lymphocyte ratio (dNLR) predicts negative appendectomy in acute appendicitis.
Retrospective observational study design
Analyzed data from 669 patients who underwent appendectomy for acute appendicitis
Compared preoperative dNLR and complete blood count parameters between negative and positive appendectomy groups
Utilized receiver operating characteristic (ROC) curve analysis to assess diagnostic performance of dNLR
Negative appendectomy rate was 20.3%
The negative appendectomy group had significantly lower dNLR and leukocyte counts compared to positive groups
dNLR showed potential as a diagnostic marker across histopathological classifications

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Implication

Retrospective study evaluates derived neutrophil-to-lymphocyte ratio in acute appendicitis, suggesting its diagnostic relevance.

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Cite This Study

Ogut et al. (2026) studied this question.

synapsesocial.com/papers/69be35e66e48c4981c674759 https://doi.org/10.32322/jhsm.1835033

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Diagnostic Value of the Derived Neutrophil-to-Lymphocyte Ratio for Acute Appendicitis2024 · 1 citations
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