Pilot randomized controlled trial demonstrates high feasibility and safety of a mind-body intervention in older adults, indicating its potential for wider application.
INTRODUCTION Aging populations require scalable, accessible, and inclusive lifestyle interventions that address multiple modifiable dementia risk factors. METHODS The REMIND er pilot randomized controlled trial, randomized (1:1) healthy older adults (≥ 60 years, retired) to a 6‐week online multimodal mind–body group intervention or a delayed‐intervention control group. The live‐streamed, home‐based, two 1‐hour sessions/week program integrates music, dance movement, and mindfulness via video conferencing. Primary outcomes were feasibility (adherence benchmark: ≥ 60%) and changes in mental and physical well‐being (Health‐Survey SF‐12). Secondary outcomes comprised feasibility metrics and safety. RESULTS Intention‐to‐treat analyses included 68 participants (mean [standard deviaton {SD}] age: 69.2 [5.2] years; 80.9% women). Mean (SD) adherence was 80% (30%), exceeding the predefined benchmark ( p = 0.010). There were no group differences in SF‐12 mental ( p = 0.827) or physical well‐being ( p = 0.656) from pre‐to‐post intervention. Feasibility was high, with 95% reach, 90% retention, and 9% dropout. No serious adverse events occurred. DISCUSSION The scalable, accessible online multimodal intervention is feasible and safe for older adults. TRIAL REGISTRATION ClinicalTrials.gov (Identifier: NCT06530277) on July 27, 2024. https://clinicaltrials.gov/study/NCT06530277 .
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