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This investigation measures corneal oxygen responses under varying lens conditions, indicating significant differences based on lens type.
Equivalent oxygen (E.O.P.) responses, using a mammalian corneal model, were measured for open‐ and closed‐eye conditions, and with and without the presence of a silicone. a standard thickness HEMA, and an ultrathin HEMA contact lens. Under open‐eye conditions, the silicone lens even with a center thickness of 0.25 mm, diminished the E.O.P. response insignificantly compared to the no‐lens condition. The ultrathin HEMA lens (0.06‐mm center thickness) produced a response approximately three times superior to that of the standard thickness HEMA lens. Under closed‐eye conditions, only the silicone lens, however, caused the cornea to respond within the Polse‐Mandel zone.
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ROSCOE et al. (1980) studied this question.
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